Interferon induction by radioprotective mercaptoalkylamines and derived thiophosphates
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چکیده
منابع مشابه
Interferon induction by adenoviruses.
All human, simian, bovine and avian adenovirus types tested so far and the canine hepatitis virus induce interferon production in chick cells. This finding indicated this property to be characteristic for viruses belonging to the adenovirus group. Trypsin treatment, which had no effect upon the infectivity, diminished or eliminated the interferon-inducing abilities of crude adenoviruses, and th...
متن کاملInterferon Induction by Viruses
Interferons are proteins of cellular origin capable of conferring virus resistance to vertebrate cells. Most cells do not produce interferons except in response to proper stimulation. Clearly, the stimulation of interferon production encompasses two phenomena. When stimulated, some cell systems produce their interferons by synthesizing new proteins. Other cell systems do not require the synthes...
متن کاملInterferon Induction by RNA Viruses and Antagonism by Viral Pathogens
Interferons are a group of small proteins that play key roles in host antiviral innate immunity. Their induction mainly relies on host pattern recognition receptors (PRR). Host PRR for RNA viruses include Toll-like receptors (TLR) and retinoic acid-inducible gene I (RIG-I) like receptors (RLR). Activation of both TLR and RLR pathways can eventually lead to the secretion of type I IFNs, which ca...
متن کاملMolecular Aspects of Interferon Induction by Viruses
Virus-induced interferon formation depends on the presence within the cell of a viral ribonucleic acid. This RNA may either be double stranded or, in certain cases, single stranded. The double-stranded RNA can be derived from a virus, such as reovirus, which contains this type of RNA, or it may be synthesized within the cell using viral single-stranded RNA as a template. Single-stranded RNA mus...
متن کاملInterferon induction by bluetongue virus and bluetongue virus ribonucleic acid.
EKSTEEN, P. A . L. & HUISMAN S, H. Interferon induction by bluetongue virus and bluetongue virus ribonucleic acid. Onderstep oort]. vet . R es. 39(3), 125-132 (1972). The stimulation of interferon synthesis by bluetongue virus and by bluetongue virus ribonucleic acid was investigated in order to determine if there is a difference in the mechanism of induction. The molecular mass of the interfer...
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ژورنال
عنوان ژورنال: Infection and Immunity
سال: 1977
ISSN: 0019-9567,1098-5522
DOI: 10.1128/iai.15.1.191-196.1977